Women's Plus Size Cotton Pajamas

Womens plus-size cotton pajamas make it easy to relax and unwind in comfort, whether you’re starting your morning or settling in for the night. Crafted with soft, breathable cotton and designed for lasting comfort, these pajamas offer a timeless style that feels just right. With a range of colors and patterns to choose from, you’ll find options that suit your everyday routine and bring a little extra coziness to every moment.

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298 Items

Women's Scotch Plaid Flannel Pajamas

A cozy blue plaid pajama set crafted from ultrasoft Portuguese cotton flannel for lasting warmth and comfort.
Women's Cozy PJ Set

A soft, breathable 100% cotton flannel pajama set in faded rose plaid with contrast trim.

Pros: Fit Quality Comfort Cute print Warmth
Women's Cozy PJ Set, Print

A red flannel pajama set featuring exclusive prints, soft cotton fabric, and a comfortable henley top.
Women's L.L.Bean Camp PJ Set
Price was from: $89.95 now: $64.99

A super comfortable PJ set with a pink sandstone dog print, featuring a flannel pant and cotton top.

Pros: High quality Warmth Softness Comfortable Cute design
Women's Super-Soft Shrink-Free Pajama Set, Button-Front

A gray cotton-blend pajama set featuring a button-front top and relaxed pants with adjustable drawstring.
Women's Supima Nightgown, Short-Sleeve

A silky-soft blue nightgown made from 100% Supima cotton with a feminine scoopneck and shirring details.

Pros: Attractive color and style Flattering fit Exceptional comfort Soft Supima cotton fabric Durable and easy to care for
Women's Super-Soft Shrink-Free Button Front Pajama Set, Stripe

A super-soft, shrink-free cotton blend pajama set in classic navy and cream stripes with adjustable drawstring pants.

Pros: True to size High-quality fabric Breathable material Super soft Comfortable fit
Women's Super-Soft Shrink-Free Pajamas, Short Set

A blue cotton-blend pajama short set featuring a button-front top and adjustable drawstring shorts.

Pros: Super-soft fabric High quality Exceptional comfort
Women's Soft Waffle Sleep Set

A cozy blue cotton-blend waffle pajama set with wide-leg pants, elastic waistband, and split-neck top.
Women's Bean's Seacoast Seersucker Short Set

An airy pink seersucker short set in a cotton blend with a relaxed fit and adjustable waist.
Women's Super-Soft Shrink-Free Pajamas, Short Set Stripe
Price was from: $79 now: $64.99

A pink striped pajama short set in a supersoft cotton blend with contrast piping and adjustable waistband.
Women's Scotch Plaid Flannel Nightgown

A cozy red plaid nightgown made from ultrasoft 100% Portuguese cotton flannel with on-seam pockets.
Women's L.L.Bean Flannel Sleep Pants, Plaid

A pair of red plaid flannel pajama pants made from soft, 100% cotton with adjustable drawstring.
Women's L.L.Bean Flannel Sleep Pants, Print

A pair of cozy blue flannel pajama pants with vibrant prints, adjustable drawstring, and on-seam pockets.
Women's Supima Cotton Nightgown, V-Neck Three-Quarter-Sleeve

A relaxed-fit nightgown in lake blue, made from 100% ultrasoft Supima cotton with a feminine V-neckline.
Women's Restorative Sleepwear Sleep Pants
Price was from: $64.95 now: $54.99

A pair of incredibly soft, navy wide-leg sleep pants with a comfortable elastic waistband and side seam pockets.

Pros: Well-made Lightweight Softness Comfortable waistband Good fit
Women's Restorative Sleepwear Sleep Pants, Print
Price was from: $69.95 now: $59.99

A pair of blue wide-leg sleep pants in a soft cotton-modal blend with a butterfly hem.

Pros: Versatile design Durable material Good value Soft fabric Comfortable fit
Women's Restorative Sleepwear, Long-Sleeve Henley
Price was from: $59.95 now: $49.99

A soft, lightweight cotton blend long-sleeve Henley sleep top in classic navy with a relaxed fit.
Women's Daybreak Nightgown
Price was from: $59.95 now: $24.99

A light and airy white dot nightgown made of 97% cotton and 3% spandex with side seam pockets.
L.L.Bean Flannel Sleep Pants, Plaid Fleece-Lined
Price was from: $79 now: $54.99

A pair of pink fleece-lined cotton flannel pajama pants with vibrant plaid and adjustable drawstring waist.
Women's Restorative Sleepwear, Long-Sleeve Henley Print
Price was from: $69.95 now: $44.99

A soft, lightweight long-sleeve sleep top in sailcloth stripe, made from a 50% pima cotton and 50% modal blend.

Women's Plus Size Cotton Pajamas

When it comes to winding down after a busy day, there’s nothing quite like slipping into a pair of soft, well-made cotton pajamas. For many women, especially those seeking plus sizes, finding the right pajamas is about more than nighttime comfort—it’s about feeling relaxed, confident, and at ease in your own skin. Cotton pajamas are a timeless choice, beloved for their breathability and gentle touch, especially during the warmer months of June and beyond. Whether you’re curling up with a good book on a breezy summer evening, enjoying a leisurely morning with a cup of coffee, or simply settling in for a restful night’s sleep, the right cotton pajamas can make all the difference. The natural fibers of cotton help keep you cool as temperatures rise, wicking away moisture and allowing your skin to breathe, so you can focus on what matters: unwinding and recharging.

Thoughtfully designed plus size cotton pajamas aren’t just about comfort—they’re about versatility and lasting value. Many women find that the right pajamas become their go-to loungewear, perfect for those cozy moments spent with family or friends, or for catching up on your favorite shows. They also make a thoughtful gift for birthdays, holidays, or simply as a gesture of care, offering loved ones the simple pleasure of comfort that lasts. When choosing plus size cotton pajamas, consider details like easy-to-use closures, smooth seams, and non-binding waistbands, all of which contribute to a better fit and a more restful night. Look for timeless styles and classic patterns that never go out of style, ensuring your pajamas will be a favorite season after season. And if you’re shopping for someone else, think about what makes their downtime special—perhaps it’s a quiet morning on the porch or a movie night at home—and choose pajamas that will help them enjoy those moments even more.

Quality cotton pajamas are built to handle everyday wear, wash after wash, maintaining their softness and shape over time. They’re easy to care for, too—just toss them in the laundry and they’re ready for another round of relaxation. Whether you’re treating yourself or searching for a thoughtful gift, it’s worth exploring options designed with comfort, durability, and ease of use in mind. For a wide selection of styles and sizes, including options made from the softest cotton blends, take a look at the Womens Soft Cotton Pajamas collection. Here you’ll find pajamas that feel as good as they look, ready to help you make the most of every restful moment, season after season.