Women's Plus Size Cotton Pajamas

Womens plus-size cotton pajamas make it easy to relax and unwind in comfort, whether you’re starting your morning or settling in for the night. Crafted with soft, breathable cotton and designed for lasting comfort, these pajamas offer a timeless style that feels just right. With a range of colors and patterns to choose from, you’ll find options that suit your everyday routine and bring a little extra coziness to every moment.

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298 Items

Women's Cozy PJ Set

A soft, breathable 100% cotton flannel pajama set in faded rose plaid with contrast trim.

Pros: Fit Quality Comfort Cute print Warmth
Women's Cozy PJ Set, Print

A red flannel pajama set featuring exclusive prints, soft cotton fabric, and a comfortable henley top.

Pros: True to size with great fit High quality, durable fabric Cute prints and attractive design Exceptionally cozy and comfortable Warm and perfect for colder weather
Women's L.L.Bean Camp PJ Set
Price was from: $89.95 now: $54.99

A super comfortable PJ set with a pink sandstone dog print, featuring a flannel pant and cotton top.

Pros: High quality Warmth Softness Comfortable Cute design
Women's Super-Soft Shrink-Free Pajama Set, Button-Front

A gray cotton-blend pajama set featuring a button-front top and relaxed pants with adjustable drawstring.

Pros: Exceptionally soft fabric Does not shrink or wrinkle Washes well and maintains quality Very comfortable to wear Fits well and true to size
Women's Super-Soft Shrink-Free Button Front Pajama Set, Stripe

A super-soft, shrink-free cotton blend pajama set in classic navy and cream stripes with adjustable drawstring pants.

Pros: True to size High-quality fabric Breathable material Super soft Comfortable fit
Women's Soft Waffle Sleep Set

A cozy blue cotton-blend waffle pajama set with wide-leg pants, elastic waistband, and split-neck top.
Women's Super-Soft Shrink-Free Pajamas, Short Set Stripe
Price was from: $79 now: $54.99

A pink striped pajama short set in a supersoft cotton blend with contrast piping and adjustable waistband.
Women's L.L.Bean Flannel Sleep Pants, Plaid

A pair of red plaid flannel pajama pants made from soft, 100% cotton with adjustable drawstring.

Pros: Attractive colors and patterns Exceptionally soft and cozy Warm and perfect for winter High quality and durable fabric Great fit and adjustable waist
Women's Supima Cotton Nightgown, V-Neck Three-Quarter-Sleeve

A relaxed-fit nightgown in lake blue, made from 100% ultrasoft Supima cotton with a feminine V-neckline.

Pros: Exceptionally comfortable Soft and high-quality cotton fabric Flattering and true-to-size fit Lightweight and ideal for warm weather Retains shape and durability after washing
Women's Restorative Sleepwear Sleep Pants, Print
Price was from: $69.95 now: $49.99

A soft, lightweight cotton blend sleep pant with a butterfly hem and comfortable elastic waistband.

Pros: Versatile design Durable material Good value Soft fabric Comfortable fit
L.L.Bean Flannel Sleep Pants, Plaid Fleece-Lined
Price was from: $79 now: $44.99

A pair of pink fleece-lined cotton flannel pajama pants with vibrant plaid and adjustable drawstring waist.

Women's Plus Size Cotton Pajamas

There’s something undeniably comforting about slipping into a pair of soft cotton pajamas at the end of a long day. For many, it’s a cherished nightly ritual—changing out of the day’s clothes and into something thoughtfully made, designed for relaxation and true comfort. Women’s plus size cotton pajamas are a favorite for good reason: the gentle touch of breathable cotton against your skin, the easy drape that moves with you, and the way they hold up wash after wash make them a timeless staple for winding down. As September brings its first hints of coolness to the air, these pajamas become even more inviting. Whether you’re curling up with a favorite book, sharing stories with family, or simply enjoying a quiet moment before bed, cotton pajamas help create a space of ease and warmth. Their versatility shines through, too—they’re just right for lazy weekend mornings, working from home, or packing for a cozy getaway.

Thoughtfully designed plus size cotton pajamas are all about lasting value and everyday practicality. When choosing a set, it’s worth paying attention to details like smooth seams that won’t chafe, elastic waistbands that stay comfortable through the night, and well-placed pockets for those little essentials. The best pajamas balance durability with softness, holding their shape and color over time so you can count on them season after season. They also make a heartfelt gift—ideal for birthdays, holidays, or just because—offering a gesture of care and comfort that feels personal and thoughtful. For anyone who appreciates easygoing style and a relaxed fit, these pajamas are a welcome addition to the nightly routine. The inclusive sizing ensures that everyone can find a pair that suits their needs, making bedtime or lounging around the house a little more enjoyable.

There’s a special kind of satisfaction in finding pajamas that feel just right—ones that you reach for again and again, whether you’re settling in after a busy day or savoring a slow morning. Cotton’s natural breathability makes these pajamas especially comfortable as the seasons shift, keeping you cool on lingering warm nights and cozy as autumn breezes arrive. They’re easy to care for, too, so you can spend more time enjoying your evenings and less time worrying about upkeep. For anyone seeking a blend of classic style, comfort, and quality, Womens Soft Cotton Pajamas are a reliable choice—crafted to make every night and morning feel a little more special. Whether you’re shopping for yourself or looking for a thoughtful gift, these pajamas are designed to help you relax, recharge, and enjoy the simple pleasures of home.