Cotton Blend Pajamas

Cotton blend pajamas offer the perfect combination of comfort and durability for a restful night's sleep. Crafted to provide lasting value, these pajamas are designed with your relaxation in mind, making them an essential addition to your nightly routine. The soft, breathable fabric ensures you stay cozy throughout the night while maintaining a timeless style that suits everyone. Whether you're lounging at home or settling in for a good night's rest, our versatile cotton blend pajamas are sure to become your go-to choice for ultimate comfort and ease.

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298 Items

Men's Scotch Plaid Flannel Pajamas

A pair of ultrasoft 100% cotton flannel pajamas in black watch tartan, featuring a relaxed fit and elastic waistband.

Pros: High quality Attractive design Perfect fit Soft and comfortable Warmth
Women's L.L.Bean Camp PJ Set

A cozy red plaid PJ set with a flannel pant and jersey-knit cotton top, featuring exclusive graphics.

Pros: High quality Warmth Softness Comfortable Cute design
Women's Super-Soft Shrink-Free Pajama Set, Button-Front

A bright navy, shrink-free pajama set in a supersoft cotton blend with adjustable drawstring pants.

Pros: No shrinkage True to size Comfortable Super soft Adjustable drawstring waist
Women's Super-Soft Shrink-Free Button Front Pajama Set, Stripe

A super-soft, shrink-free cotton blend pajama set in classic navy and cream stripes with adjustable drawstring pants.

Pros: True to size High-quality fabric Breathable material Super soft Comfortable fit
Women's Restorative Sleepwear Sleep Pants, Print
Price was from: $69.95 now: $49.99

A soft, lightweight cotton blend sleep pant with a butterfly hem and comfortable elastic waistband.

Pros: Versatile design Durable material Good value Soft fabric Comfortable fit
Daybreak Pajama Set
Price was from: $74 now: $44.99

A cozy arctic blue pajama set with a soft-knit cotton top and cotton-spandex drawstring pants.
Women's Soft Waffle Sleep Set

A cozy blue cotton-blend waffle pajama set with wide-leg pants, adjustable waistband, and split-neck top.
Women's Bean's Seacoast Seersucker Pajama Pant Set

A comfy sleep set with a soft-knit scoopneck top and airy seersucker pants with pockets.
Men's Bean's Cotton Knit Pajamas, Button-Front PJ Set

A classic black pajama set crafted from soft 80% cotton and 20% recycled cotton interlock knit.
Women's Bean's Seacoast Seersucker Short Set
Price was from: $64.95 now: $44.99

An airy seersucker short set in a cotton-modal blend with a relaxed fit and button-front shirt.
Men's Bean's Cotton Knit Pajamas, Henley PJ Set

A supersoft henley pajama set made from 80% cotton and 20% recycled cotton in gray heather.
Women's Super-Soft Shrink-Free Pajamas, Short Set Stripe
Price was from: $79 now: $54.99

A striped multi-color pajama short set in a supersoft, shrink-free cotton blend with contrast piping.
Women's Restorative Sleepwear, Long-Sleeve Henley Print
Price was from: $69.95 now: $39.99

A lightweight, chalk blue geo sleep top made from a soft 50% pima cotton and 50% modal blend.
Men's Wicked Cozy Flannel Sleep Pant

A pair of flannel sleep pants in deepest indigo charging moose, made from a soft cotton blend.
Women's Scotch Plaid Flannel Pajamas

A pair of ultrasoft Portuguese cotton flannel pajamas in black watch plaid, featuring a relaxed fit and adjustable drawstring.

Pros: Fit Quality Comfort Softness Warmth
Women's Cozy PJ Set

A 100% cotton flannel pajama set in faded rose plaid with a henley neckline and contrast trim.

Pros: Fit Quality Comfort Cute print Warmth
Women's Cozy PJ Set, Print

A soft, breathable cotton pajama set in ocean teal dog print with a henley top and flannel pants.

Pros: Perfect fit Quality Comfort Cute print Warmth
Women's Supima Cotton Nightgown, V-Neck Three-Quarter-Sleeve

A relaxed blue nightgown crafted from ultrasoft Supima cotton with three-quarter sleeves and a feminine V-neck.

Pros: Lightweight material True to size Retains shape Soft cotton fabric Comfortable fit
Women's Restorative Sleepwear Sleep Pants
Price was from: $64.95 now: $44.99

A pair of lavender ice wide-leg sleep pants made from a soft 50% pima cotton and 50% modal blend.

Pros: Lightweight Comfortable waistband Durable Good fit Soft fabric
Men's Bean's Cotton Knit Pajamas, Sleep Pants

A pair of dark black heather sleep pants made from 80% cotton and 20% recycled cotton.

Pros: Outdoor use Quality Comfort Value

Cotton Blend Pajamas

When it comes to winding down after a busy day or enjoying a slow weekend morning, nothing feels quite as comforting as slipping into a well-made pair of cotton blend pajamas. The unique blend of cotton with other fibers brings together the best of both worlds: the familiar softness and breathability of cotton, paired with added durability and easy-care qualities that help pajamas hold their shape and color through countless washes. Whether you’re curling up with a good book, sharing popcorn during a family movie night, or savoring that first cup of coffee on the porch as the sun rises, cotton blend pajamas are designed to make those moments even cozier. Their lightweight feel makes them an ideal choice as the weather warms up in May, helping you stay cool and comfortable through the night, while still providing just enough warmth for those lingering spring breezes.

Cotton blend pajamas are a thoughtful and practical gift for anyone who values comfort and relaxation—whether you’re shopping for a high school graduate heading off to college, a friend celebrating a birthday, or a family member who deserves a little extra pampering. Their timeless styles and inclusive sizing options mean there’s something for everyone, from kids eager to pick out their favorite patterns to adults looking for classic designs that never go out of style. These pajamas are just as at home during a festive sleepover as they are during a quiet evening spent catching up with loved ones over video calls. For those who appreciate the simple joys of everyday life—like the fresh scent of laundry, the feel of crisp sheets, or the gentle rustle of leaves outside an open window—cotton blend pajamas become a cherished part of the nightly routine. If you’re searching for comfortable and versatile sleepwear, explore our collection of Women's Cotton PJs to find your new favorites.

Choosing the right pair of pajamas often comes down to personal comfort and practical needs. Cotton blend fabrics are beloved for their easy care and lasting value, resisting wrinkles and shrinkage while maintaining a soft touch wash after wash. They’re designed to move with you, stretching gently as you reach for the remote or tuck in the kids, and they’re crafted to stay comfortable on both cool spring nights and balmy summer mornings. Many families find themselves reaching for cotton blend pajamas not just at bedtime, but throughout the day—whether for a lazy Sunday breakfast, a quick dash to the mailbox, or even a relaxing afternoon nap. With a variety of styles, colors, and patterns to choose from, it’s easy to find pajamas that reflect your personality and fit seamlessly into your daily routine. Ultimately, cotton blend pajamas are more than just sleepwear—they’re an invitation to slow down, unwind, and enjoy the little things that make home feel special.

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Cotton Blend Pajamas